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【Product Introduction】 

Aloe-emodin is an anthraquinone compound, an antibacterial active ingredient of rhubarb, a kind of orange needle-like crystals (toluene) or ocher crystalline powder (ethanol), which can be extracted from aloe. Anti-tumor activity, antibacterial activity, immunosuppressive effect, and diarrhea effect, it is now widely used as a raw material for medicines, health products and cosmetics.

【Product Alias】 Aloe diarrhea

【Specifications】: 50%, 95%

【Appearance】: orange needle-like crystal or ochre crystalline powder

【Plant Source】: Aloe vera (L.) Burm.f.

【Test Method】: HPLC

【CAS Number】481-72-1

【Chemical Name】1.8-Dihydroxy-3-[hydroxymethyl]-anthraquinone

【Molecular Formula】C15H10O5

【Molecular Weight】270.23

【Product Function】

1. Anti-tumor effect

In recent years, scholars at home and abroad have been interested in the anti-tumor effect of aloe-emodin. Its main anti-tumor activity is concentrated on neuroectodermal tumors, liver cancer, lung squamous cell carcinoma, skin Merkel cell carcinoma, gastric cancer, leukemia and other tumors. It has a wide range of anti-cancer effects. Aloe-emodin has an inhibitory effect on P388 leukemia cells and can prolong survival. One of its mechanism of action is to inhibit the biosynthesis of DNA, RNA and protein in cancer cells.

2. Antibacterial effect

Aloe-emodin has inhibitory effects on Staphylococcus, Streptococcus, Bacillus diphtheria, Bacillus subtilis, anthrax, Bacillus paratyphi, Bacillus dysentery, etc. One of its mechanism of action is to inhibit electron transmission in the mitochondrial respiratory chain. Aloe-emodin has a strong inhibitory effect on the nucleic acid and protein synthesis of Staphylococcus aureus, and also has a strong inhibitory effect on clinically common anaerobic bacteria.

3. Intestinal laxative effect

Aloe-emodin has a strong effect of increasing appetite and laxative effects of large intestine. According to foreign medical reports, aloin is hydrolyzed into aloe-emodin under the action of parasitic bacteria in the human body. This aloe-emodin stimulates the peristalsis of the intestinal wall. At the same time, due to the change of osmotic pressure, it is beneficial to the elimination of waste in the intestine, thereby achieving irritation. Laxative, this stimulating and purging effect has a special effect on constipation and hemorrhoids. Especially for middle-aged and elderly constipation, the treatment effect is more obvious.

4. Suppress immune hyperactivity

Immune abnormality can cause damage to the body. For example, many autoimmune diseases are caused by abnormal expression of autoimmunity, and normal tissues of the body are regarded as the target of attack, causing damage to the body. The use of aloe-emodin can inhibit the production of antibodies in the organism, thereby suppressing immunity Excessive (anti-allergic).

5. Lipid-lowering and weight-loss effect

Aloe-emodin can inhibit the absorption of cholesterol, and in addition, it can effectively promote intestinal peristalsis, so it has a certain effect of reducing fat and losing weight.

【Applications】

Pharmaceutical and chemical intermediates;

Health food additives;

Cosmetic raw materials and hair care raw materials.