• 
• 

【Product Description】

Kaempferol is extracted from the dried and mature fruits of Sophora Japonica L. FocusHerb strictly controls the quality of the raw materials and the entire production process, and the raw materials meet the pharmacopoeia standards.

【Product Name】 Kaempferol

【Specifications】30%~98%

【Appearance】 Yellow fine powder

【Extraction Source】 The fruit of Sophora japonicus

【Test Method】HPLC

【Product Alias】Tetrahydroflavonoids, Kaempferol-3

【Extraction Solvent】 Ethanol/Water

【CAS Number】520-18-3

【Molecular Formula】C15H10O6

【Molecular Weight】286.23

【Physical Properties】 Melting point 276℃-278℃. Kaempferol is slightly soluble in water, soluble in hot ethanol, ether and alkali.

【Particle Size】 100% over 80 mesh

【Recommended Addition Amount】

1. The amount of propolis added is 0.12%-0.2%

2. Recommended dosage of health care products: 15mg

【Benefits】

1. Anti-cancer

Kaempferol mainly regulates the transcription of cyclooxygenase-2, inhibits the function and expression of P-glycoprotein, inhibits interleukin-4 against cell proliferation, induces apoptosis, interferes with cell signal transduction and enhances tumor suppressor genes It has anti-cancer effects in terms of activity and inhibition of oncogene expression. Among them, it inhibits tumor cell proliferation by inducing tumor cell apoptosis.

2. Antioxidant

Kaempferol has the function of inhibiting the formation of AGE (Advanced glycation endproducts) and eliminating free radicals. It also has a strong antioxidant effect in preventing intracellular lipids and DNA oxidative damage. It can also regulate the levels of NO and NOS, and protect endothelial cells from oxidative damage by inhibiting the degradation of NO.

3. Anti-fertility, anti-osteoporosis

Kaempferol has obvious anti-fertility effects on animals and exhibits estrogen-like activity. Estrogen has a direct proliferation effect on osteoblasts, and it also has a significant promotion effect on the differentiation of osteoblasts after proliferation, so it is clinically used to prevent and treat osteoporosis.

4. Hypoglycemic effect

Kaempferol can improve diabetic endothelial dysfunction, improve the ability of microvascular lumen, effectively prevent type 2 diabetic cardiomyopathy and diabetic blood vessels, and is expected to become a new generation of insulin sensitizer.

5. Antibacterial, it has inhibitory effect on Staphylococcus aureus, Pseudomonas aeruginosa, Typhoid bacillus and Shigella bacillus.

6. Relieve cough and treat bronchitis.

7. Inhibit eye aldose reductase, which is beneficial to the treatment of diabetic cataract

8. It has mutagenic activity. When the concentration is 1×10-4mol/L, it can inhibit the proliferation of lymphocytes.

9. Anti-epileptic, anti-inflammatory, antispasmodic, anti-ulcer, choleretic and diuretic.

【Applications】 

Application and application prospects: At present, the anti-cancer effect of flavonol compounds has become a research and development hotspot for pharmaceutical workers all over the world. Kaempferol, which has a chemical structure similar to quercetin, has anti-cancer, anti-oxidation, anti-fertility and anti-bone properties. It has high medicinal value in terms of texture loss and blood sugar reduction, and has been used clinically to treat gastric cancer and cardiovascular and cerebrovascular diseases. In recent years, with the continuous improvement of the experimental level, many valuable clues have been discovered. Based on the research results of kaempferol's pharmacological effects, its wide application in clinical practice has become the focus of future research, and it also laid the foundation for broadening its application in the fields of food, health food and medicine.

Case 1: Swisse Propolis

The Swisse propolis contains kaempferol and quercetin, which are also indispensable for antifungal.

Case 2: Seabuckthorn Flavonoids

The main active ingredients are low glycosides containing isorhamnetin, isorhamnetin-3-B-D-glucoside, isorhamnetin-3-B-rutinoside, quercetin and kaempferol.

Functions: Relieve cough and expectorant, eliminate food and resolve stagnation, promote blood circulation and dissipate blood stasis.

【Advantages】 

1. Our company has focused on producing Huaijiao extract for decades, and has controlled the quality and stability of the raw materials from the source. From the entry of raw materials to the final product, we strictly follow the requirements of GMP to control to ensure product quality.

2. The company has advanced imported testing equipment to ensure traceability testing from raw materials to production.

3. The professional technical team strictly controls the quality and quality.

4. The product has no pesticide residues, low solvent residues and high purity.